Solitary Osseous Plasmacytoma of the Orbit
Keywords:
solitary bone plasmacytoma, orbital tumors, orbit, proptosisAbstract
Solitary orbital bone plasmacytoma, in the absence of multiple myeloma, is very rare. We present the case of a 60-year-old male patient who came for consultation because he noticed a painful and progressive left ocular protrusion since 3 months ago. A computed tomography was performed, which revealed an extensive ipsilateral sphenoidal osteolysis, with a slight increase in thickness and density of the neighboring soft tissue, which caused the proptosis. A possible primary neoplasm at another level was not demonstrated; while the absence of other bone lesions, anemia, Bence Jones protein in urine, bone marrow involvement, hypercalcemia and renal failure, together with normal immunoglobulin levels, excluded multiple myeloma. Therefore, the most probable diagnosis was considered to be that of a solitary bone plasmacytoma of the orbit. Subtotal resection of the lesion was performed and the diagnosis was confirmed by histopathologic examination.
Downloads
References
1. Belgacem I, Djouadi Y, Habchi N, Djaafer M. Solitary Orbital Plasmocytoma: A Case Report and Review of Literature. NNOAJ. 2020;5(2):1-3. DOI: 10.23880/nnoaj-16000153
2. Llerena-Moreno D, Quesada-Laferte Y, Arias-Galán L, Plasencia-Termblom A, Cristo-Pérez V. Plamocitoma solitario de hueso y localización múltiple. Reporte de un caso. Rev Cubana Hematol Inmunol Hemoter. 2017 [acceso 23/11/24];36(Suplemento):1-6. Disponible en: https://revhematologia.sld.cu/index.php/hih/article/view/678/717
3. Medina Pérez VM, Vasallo Díaz AL, Peñate Tamayo FD. Plasmocitoma solitario extramedular de órbita con extensión al seno maxilar. Medicent Electrón. 2017 [acceso 23/11/24];21(4):351-5. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S102930432017000400011&Ing=es&nrm=iso
4. Permaisuari N, Anggraini N, Mahyuddin M, Kodrat E, Rajabto W. A Case Series of Aggressive Orbital Plasmacytomas. Ocul Oncol Pathol 2022;8(4-6):197-202. DOI: 10.1159/000527273
5. Matos A, Goulart A, Ribeiro A, Freitas R, Monteiro C, Martins P. Orbital Plasmacytoma, An Uncommon Presentation of Advanced Multiple Myeloma. Eur J Case Rep Intern Med. 2020;7(3):001149. DOI: 10.12890/2020_001149
6. Abreu Perdomo FA, Ortiz Ramos DL, Santos Silva D, González García JL, Fernández González O, Caballero García J. Características clínicas y patológicas de los tumores orbitarios. Rev Cuban Oftalmol. 2018 [acceso 23/11/24];31(2):1-12. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21762018000200007&Ing=es&nrm=iso
7. Navarro AD, Rojas VP, Ormeño JC, Maturana BJ, Klaasen PR. Plasmocitoma extramedular solitario rinosinusal: reporte de caso y revisión de literatura. Rev Otorrinolaringol Cir Cabeza Cuello. 2022;82(3):328-332. DOI: 10.4067/s0718-48162022000300328
8. Thumallapally N, Meshref A, Mousa M, Terjanian T. Solitary plasmacytoma: population-based analysis of survival trends and effect of various treatment modalities in the USA. BMC Cancer. 2017;5;17(1):13. DOI: 10.1186/s12885-016-3015-5
9. Labrada Placeres L, Areces López A, Gámez Pérez A. Plasmocitoma óseo solitario, una gammapatía monoclonal infrecuente. Informe de un caso. Rev 16 de Abril. 2021 [acceso 23/11/24];60(282):e1456. Disponible en: https://rev16deabril.sld.cu/index.php/16_04/article/view/1456
10. Seetahal-Maraj P, Knight P, Ramnarine N. Proptosis secondary to a solitary plasmacytoma of the sphenoid bone: a case report on a rare skull base tumour. Egypt J Neurosurg. 2022;37(4). DOI: 10.1186/s41984-022-00144-2
11. Barmas-Alamdari D, Sodhi GS, Shenouda TA. Bilateral proptosis in a case of recurring multiple myeloma: uncommon orbital presentation of plasmacytoma. Int Med Case Rep J. 2020;13:297-301. DOI: 10.2147/IMCRJ.S260472
12. Kim YJ, Moon SW, Park I-K, Shin J-H. Extramedullary plasmacytoma of the orbit with intracranial invasion: A case report. Medicine 2023;102:24(e33920). DOI: 10.1097/MD.0000000000033920
13. Pyon ER, Wang CG, Chu Y, Tulpule S. Bilateral Orbital Plasmacytomas With Orbital Compartment Syndrome. Cureus. 2022;23;14(6):e26269. DOI: 10.7759/cureus.26269
14. Gómez Pérez MG. Imagen por resonancia magnética en los tumores óseos malignos. Acta Médica Grupo Ángeles. 2016 [acceso 8/12/24];14(1):S38-S44. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=68180
15. Torres Giménez F, López Lara M, Fontes Caramé D, Molina Cuadrado M, Liarte Trias I. Estudio multimodal de imagen para el diagnóstico diferencial del plasmocitoma. Imagen Diagnóstica 2010;1(2):56-60. DOI: 10.1016/S2171-3669(10)70013-5
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Revista Cubana de Oftalmología

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
El contenido de la revista se encuentra accesible sin costo alguno. Está protegido por los términos de la Licencia de Creative Commons Reconocimiento-NoComercial 4.0 Internacional